Skin Care Management System Normal Combination Skin


The 5-Step System includes:

  • Step 1 Cleanse – Bioglycolic Face Cleanser (237ml),
  • Step 2 Rejuvenate – C-ESTA Face Serum (30ml),
  • Step 3 Resurface – Bioclear Face Lotion (30ml),
  • Step 4 Hydrate – Transformation Face Cream (28g),
  • Step 5 Protect – Antioxidant Daily Face Protectant SPF33 (57g)

The date listed on Jan Marini items is the ‘sell by date’. Items can be used for their entire shelf life, even if opened after the date on their packaging.

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Skin Care Management System by Jan Marini Skin Research (JMSR) is a dramatic transformation and skin regeneration program for use at home. It was voted Best System for 10 Straight Years by NewBeauty Magazine.

Unparalleled value and superior results make the System the #1 solution for every skin type and need. 5-Step System includes five top Jan Marini products to cleanse, rejuvenate, correct, hydrate, and protect the skin with every application.

In every product and their combination, it delivers the most advanced technologies to achieve maximum results.

Individual Product Breakdown:

Cleanse: Bioglycolic Face Cleanser contains a high concentration of glycolic acid to remove dead cells and correct uneven texture while effectively melting all traces of bacteria, make-up, and impurities from the surface of the skin.
It is a gentle cleanser that encourages a softer, smoother, and more refined skin texture.
Its mild non-irritating formula is soap-free. It rinses completely without the need for a post-cleansing.

Rejuvenate: C-ESTA Face Serum is a powerful anti-aging antioxidant cocktail, featuring Vitamin C and DMAE, proved to reduce the appearance of fine lines and wrinkles and uneven skin texture.
Lightweight serum quickly penetrates the skin to target all signs of aging. The skin’s appearance will become smoother and suppler and will feel firmer and much more resilient. Facial contour will appear tighter and more defined, whereas deeper lines will appear less pronounced. Skin tone will also even out, making the skin’s appearance noticeably younger and healthier.

Resurface: Bioclear Face Lotion has remarkable anti-aging and skin resurfacing properties. It is also especially beneficial for adult acne.
If you are concerned about common skin issues such as fine lines and wrinkles, acne, rosacea, acne scarring, large follicles, and skin texture changes, Bioclear is an exceptional solution.
Bioclear Cream provides dramatic resurfacing and retexturizing benefits on any skin type resulting in measurably smoother, clearer and younger-looking skin.
It utilises a combination of Glycolic Acid, Salicylic Acid, and blend of powerful antioxidants with plant extracts.

Hydrate: Transformation Face Cream is a powerful anti-aging technology that combines two newly developed Peptides with Growth Factor.
It allows skin cells to produce more collagen and elastin that results in significant improvements of all signs of aging. It minimises fine lines and wrinkles, improves skin firmness and elasticity.
The skin is visibly smoother with a silky feeling surface.

Protect: Antioxidant Daily Face Protectant SPF 33 provides broad-spectrum UVA and UVB protection to decrease the risk of premature skin aging.
A sunscreen you’ll love to wear – this invisible, hydrating and weightless sunscreen feels amazing and smells great for the ultimate in daily wearability.
This fast-absorbing, cosmetically elegant formula features cutting edge microscopic sponges for additional oil control.

Dermatologists approved

Key Benefits

  • Award winning 5 step skin management system
  • Significantly minimises fine lines and wrinkles
  • Medically validated solution for all signs of aging
  • Clears acne, improves rosacea and skin discoloration
  • Groundbreaking technologies and active ingredients
  • Ideal for normal and combination skin

IDEAL FOR: Fine Lines and Wrinkles, Sagging Skin, Acne, Rosacea and Skin Discoloration, Large Pores, Acne Scarring, Enlarged Follicles, Sun Damage

SKIN TYPE: Aging, Mature, Normal and Combination, Acne-Prone Skin

Key ingredients:


Bioglycolic Face Cleanser:

Glycolic Acid 12%: Removes dead skin cells, dirt, and oil that can clog and stretch pores. Therefore, making it an excellent ingredient as an exfoliant with exceptional anti-aging properties.

Sorbitol: A natural humectant derived from berries. It leaves the skin soft and hydrated preventing it from moisture loss.


C-ESTA Face Serum:

Ascorbyl Palmitate 7% (Vitamin C): Is a potent antioxidant that neutralises free radicals and aids in skin's natural regeneration process, which helps to repair damaged skin cells.

DMAE: Increases the appearance of firmness, tone, and lift to the skin. DMAE also improves the skin elasticity and luminosity, helping to decrease the look of fine lines and wrinkles while brightening skin's appearance and evening out imperfections.


Bioclear Face Lotion:

Glycolic Acid 12%: Removes dead skin cells, dirt, and oil that can clog and stretch pores. Therefore, making it an excellent ingredient as an exfoliant with exceptional anti-aging properties.

Salicylic Acid 2%: Dissolves the skin debris that clogs pores and causes acne. It purifies skin and helps to reduce redness.

Plant Extracts: Contain healing properties. With the help of antioxidants, minerals, and vitamin components, plant extracts bring hydration to the skin and soothe irritation.

Antioxidants: Protect against environmental and UV damage, help to calm cellular inflammation caused by oxidative stress and free radicals.


Transformation Face Cream:

TGF-1 (transforming growth factor), Vascular Endothelial Growth Factor: Responsible for supporting the repair of damaged skin, making components that provide firmness and elasticity to the skin. It also aids to maintaining skin's protective functions.

Thymosin 4 (sh-Oligopeptide-4): It speeds wound healing and aids in skin repair.

Peptides: Myristoyl Pentapeptide-8 & Myristoyl Pentapeptide-11: Highly bioavailable lipo oligopeptides with anti-aging function, which accelerates the repair of damaged skin, helps to rebuild the skin's protective barrier, resists aging and reduces the appearance of fine lines.

Hyaluronic Acid: Demonstrates exceptional hydrophilic properties. It attracts and binds up to 1800 times its molecular weight in water. Hyaluronic acid also protects the skin from UVB rays, which can cause sunspots.

Beta Glucan (Yeast Extract): Works twofold to soothe and calm irritated skin and as an effective anti-ager to firm and plump fine lines and wrinkles.

Antioxidants: Neutralises environmental damage, helps diminishing the signs of aging and calms irritation.

Plant Extracts: Contains healing properties. With the help of antioxidants, minerals, and vitamin components, plant extracts bring hydration to the skin and soothe irritation.


Antioxidant Daily Face Protectant SPF33: 

Parsol 1789: This is a very strong and efficient UVA absorber.

Beta Glucan 1,3: Soothes and calms irritated skin, firms and plumps fine lines and wrinkles.

Microscopic Sponges: Works as a microsponges absorbing excessive oil.

Phytomelanin: Provides anti-aging benefits and add further protection against damage caused by UV exposure.

Hyaluronic Acid: Demonstrates exceptional hydrophilic properties. It attracts and binds up to 1800 times its molecular weight in water. Hyaluronic acid also protects the skin from UVB rays, which can cause sunspots.



Bioglycolic Face Cleanser:
Water/Aqua/Eau, Glycolic Acid, Sorbitol, Cetyl Alcohol, Stearyl Alcohol, Sodium Hydroxide, Ammonium Lauryl Sulfate, Palmitic Acid, Caprylyl Glycol, Ethylhexylglycerin, Hexylene Glycol, Phenoxyethanol.

C-ESTA Face Serum:
Water/Aqua/Eau, Ascorbyl Palmitate, Urea, Butylene Glycol Dicaprylate/Dicaprate, Dimethicone, Acetyl Tyrosine, Dimethyl MEA, Fragrance (Parfum), Zinc Sulfate, Sodium Hydroxide, Tocopheryl Acetate, Panthenol, Sodium Hyaluronate, Ergothioneine, Pyridoxine HCl, Sodium Metabisulfite, Sodium Sulfite, Xanthan Gum, Disodium EDTA, Citric Acid, Farnesol, Linalool, Amyl Cinnamal, Benzyl Salicylate, Cinnamal, Limonene, Eugenol, Gerianol, Hydroxycitronellal, Butylphenyl Methylpropional, Caprylyl Glycol, Ethylhexylglycerin, Hexylene Glycol, Phenoxyethanol.

Bioclear Face Lotion:
Water/Aqua/Eau, Butylene Glycol, Glycolic Acid, Salicylic Acid, Azelaic Acid, Sodium Hydroxide, Polysorbate 20, Sodium Hyaluronate, Undecanedioic Acid, Sebacic Acid, Suberic Acid, Sclerotium Gum, Hydroxyethylcellulose, Phenoxyethanol.

Transformation Face Cream:
Water/Aqua/Eau, Glycerin, Hexyl Laurate, Caprylic/Capric Triglyceride, Butylene Glycol, Polysorbate 60, Stearyl Alcohol, Palmitic Acid, Sorbitan Stearate, Aloe Barbadensis (Aloe Vera) Leaf Juice, Nylon-12, Sodium Hyaluronate, Myristoyl Pentapeptide-8, Myristoyl Pentapeptide-11, sh-Polypeptide-22, sh-Polypeptide-9, sh-Oligopeptide-4, Saccharomyces Cerevisiae (Yeast) Extract, Retinyl Palmitate, Tocopherol, Ascorbyl Palmitate, Ascorbic Acid, Citric Acid, Tocopheryl Acetate, Tocopheryl Linoleate, Squalane, Dimethicone, Sodium PCA, C12-20 Acid PEG-8 Ester, Cetyl Alcohol, PEG-8, Hydrolyzed Elastin, Hydrogenated Lecithin, Glycine Soja (Soybean) Oil, Sodium Oleate, Tocopheryl Oleate, Fragrance (Parfum), Amyl Cinnamal, Benzyl Salicylate, Butylphenyl Methylpropional, Eugenol, Geraniol, Limonene, Linalool, Disodium EDTA, Phenoxyethanol, Diazolidinyl Urea, Imidazolidinyl Urea.

Antioxidant Daily Face Protectant SPF33:
Avobenzone-1%, Octinoxate-7.5%, Octisalate-5%, Oxybenzone (CAS 131-57-7)-6% Inactive Ingredients: Water/Aqua/Eau, C12-15 Alkyl Benzoate, Butylene Glycol, Butyloctyl Salicylate, Cyclopentasiloxane, Cyclohexasiloxane, Phoenix Dactylifera (Date) Extract*, Sodium Lactate, Sodium Hyaluronate, Glycerin, Carbomer, Lauryl Methacrylate/Glycol Dimethacrylate Crosspolymer, Yeast Extract, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Sorbitan Oleate, Polysorbate 20, Triethanolamine, Fragrance (Parfum), Disodium EDTA, Phenoxyethanol, Imidazolidinyl Urea, Diazolidinyl Urea, Caramel, Yellow 5 (CI 19140).





Start with the Bioglycolic Facial Cleanser by massaging a generous amount into damp skin and rinsing with warm water. Use once or twice a day for best results. Follow with the C-ESTA Serum in the morning or the BioClear Lotion in the evening before applying the Transformation Face Cream to the face and neck. Complete this routine by applying your chosen sunscreen to dry skin every morning

Step 1 Cleanse - Bioglycolic Face Cleanser:
Massage 1 pump onto dry skin. Leave on the skin for a few minutes to get to work before rinsing with warm water and patting dry. Do not use it as an eye make-up remover. It can be used once or twice daily.

Step 2 Rejuvenate - C-ESTA Face Serum:
Shake bottle well. Always apply C-Esta products to clean, dry skin. Use a small amount twice a day over the entire face, neck, and behind ears, up to eyelash line and over the brow bone. It is normal for Serum colour to darken in time. This does not affect the performance of the product. Protect the product from direct heat/sunlight.

Step 3 Resurface - Bioclear Lotion:
Cleanse the skin thoroughly before applying. Apply every night for the first week, then increasing to twice daily in the second week. The user should be aware that they are likely to experience mild stinging initially and may also experience temporary redness and flaking. If redness or flaking is extreme use every other night progressing to once daily, then twice daily.

Step 4 Hydrate - Transformation Face Cream:
Massage into clean skin every morning and evening for best results.

Step 5 Protect - Antioxidant Daily Face Protectant SPF33:
Apply 15 minutes before sun exposure reapply: after 80 minutes of swimming or sweating, immediately after towel drying and at least every 2 hours.


Patch test:
If you are new to this product or any of its ingredients, we recommend completing a patch test first.


Use of Retinol:
When using Retinol for the first time, it is important to allow the skin time to acclimatise to the active ingredient.  Apply a small amount in the evening no more than twice a week, never on consecutive evenings, for at least two weeks. If the skin hasn’t suffered any extreme irritation or redness, start to increase the number of applications gradually over a period of weeks until you reach a number your skin is comfortable with. This could range from three nights to seven nights a week. As Retinol can make the skin sensitive to sunlight, always apply a sunscreen to the skin every morning to prevent sun-induced inflammation and damage.


Use of AHAs
Products containing acids can make the skin prone to dryness and sun damage, so introduce them into your routine gradually and remember to apply sunscreen every morning to protect against UV rays.






  1. Galina

    I love this set as it combines just top products. All very good and effective. Pricewise – it’s a great saving. dermoi is always very fast in delivering things! Love it!

  2. Clair

    All products are amazing and it works better when you buy the whole set. Also very pleasant saving on cosmetics which is not cheap!

  3. Claudia

    I was always buying individual products but one day I decided to buy the whole set. The results exceeded my expectations!!! It’s much better to use the whole range – it worth all my investments!!! Skin says for me now!

  4. Helen

    It is expensive but it worth it. I love every single product and it lasts for at least 3-4 months. My skin looks so much better!

  5. Helen

    and never see fewer results. There is something special about the products of Jan Marini

  6. Miria

    Just received this set – all products smell amazing and you can say they are active! I am already very happy

  7. Gloria

    It is expensive but it is much cheaper than buying individual products and the results from 5 steps systems are much more impressive. It lasts for at least 3-4 months and it’s not so bad in terms of value for money!

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