Active Serum


iS Clinical Active serum is one of iS Clinical’s most popular products. It is a go-to for acne-prone and aging skin. This innovative multi-tasking serum provides a fast-acting, “results-oriented” formula. Active Serum smoothes away the appearance of fine lines and wrinkles and visibly evens skin tone. It also helps to treat blemish-prone skin, clean clog pores and minimise pores size. This IS Clinical one of the most potent serums has a multi-acid formula comprising of glycolic (8%), lactic (2%), salicylic (2%) and kojic acids.

15 ml
30 ml
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This powerhouse iS Clinical Active Serum is clinically proven to provide instant and long-term results and can effectively treat premature ageing, hyperpigmentation and problematic acneic skin. This serum combines botanical Sugar Cane, Bilberry and Willow Bark extracts to improve the skin’s natural exfoliation processes.

It helps to remove tired, dead skin cells and also to release pores. Mushroom Extract and Arbutin work together to balance and even out skin tone and reduce dark spots by delaying melanin production.

Use daily to achieve softer skin, to smooth away fine lines and wrinkles and to accomplish a clear and healthy complexion with reduced signs of hyperpigmentation, redness and breakouts.

Key Benefits

  • Smoothes away fine lines and wrinkles
  • Reduces the appearance of hyperpigmentation, redness, and acne
  • Softening of skin texture
  • Clearer and healthier-looking complexion

IDEAL FOR: Anti-Aging, Brightening, Acne, Hyperpigmentation, Loss of Firmness, Pre- Procedure (Use 30 days prior).

SKIN TYPES: Acne-Prone skin, Oily skin, Normal skin, Aging and Mature skin, Combination skin.

Key Ingredients:

Sugar Cane (Saccharum Officinarum) 8% - Sugar cane naturally contains glycolic acid. It removes dead skin cells, dirt and oil that can clog and stretch pores. Therefore, making it an excellent ingredient as an exfoliant.

Bilberry Fruit/Leaf Extract (Vaccinium Myrtillus) 2.0% - The bilberry extract benefits from defense against premature aging. It helps to facilitate the delivery of oxygen – rich red blood cells to all the layers of the skin. Thus, helping the skin to receive other nutrients that help maintain its elasticity and suppleness. It also acts as a skin-conditioning agent that aids in nourishing the skin and increases its vitality.

Willow Bark Extract (Salix Alba) - It contains salicylic acid, a BHA that is a natural exfoliant. It is used in many acne treatments because of its ability to deep cleanse pores and remove debris within hair follicles. It can also stimulate new cell formation.

Arbutin 1.0% - Arbutin acts as an inhibitor of tyrosinase, a key enzyme involved in melanin (pigment) production. Thus, controlling hyperpigmentation.

Mushroom Extract (Polyporus Umbellatus) Source of Kojic Acid - it also inhibits tyrosinase enzyme that is also involved with melanin production. Thereby, controlling hyperpigmentation in our skin. It is also exhibits remarkable antibacterial, antimicrobial and antibiotic properties.



Water/Aqua/Eau, Glycerin, Glyceryl Polyacrylate, Butylene Glycol, SD Alcohol 30, Saccharum Officinarum (Sugar Cane) Extract, Vaccinium Myrtillus (Bilberry) Extract, Triethanolamine, Arbutin, Salix Alba (Willow) Bark Extract, Polyporus Umbellatus (Mushroom) Extract, Menthol, Phenoxyethanol.

Sulfate-Free, Phthalate-Free, Cruelty-Free, Vegan, Dermatologist Approved, Paraben-Free



Apply sparingly to clean skin, smoothing over face and neck (or as directed). This "active" product will produce a slight tingling sensation, which should dissipate within a few minutes.

  1. Elena Reva

    I never knew that home care products could be so effective! After I tried Active Serum of IS CLINICAL I started feeling the difference even on the 1st day! Obviously I did not feel complete transformation straight away but I still felt my skin was tighter and smoother.. it’s completely different level to any other product I used before! I now feel like everyone has to switch to IS Clinical and, if you want your skin be at its best, then go for Super Serum!!!!

  2. Timea

    This product is amazing for acne, hyperpigmentation or mature skin. This will help to resurface the skin gently with its glycolic acid, lactic acid and salicylic acid to renew your skin. It will also help to prepare your skin, if you planning to have microdermabrasion. It’s a must have product, if you have acne or acne scars or hyperpigmentation.

  3. Juliet

    I think this product is amazing and would recommend it, best use at night under your moisturiser.

  4. Kate Webster

    I bought Active Serum to help me with my acne prone, after one month using it My skin got much, but much better, also all of my friends saw the changed…

    Thank you Dermoi!

  5. Tatiana

    I read a lot about this serum before I bought it – it has 4 essential acids in high proportion – Glycolic, Lactic, Salicilic & Kojic.
    All of them are hugely important for skin exfoliation and rejuvenation. It’s a very sophisticated product which skin needs and it does not cause any irritation!!!!! Fully recommend it

  6. Julia

    Have been using this product for six months at night and noticed a huge difference on lines around my eye area improving elasticity and pigmentation.I recommended it for any signs of ageing.

  7. Ella

    The results are incredible and I felt different from the 1st day!

  8. Thalia

    This serum really is a miracle worker. It has completely changed my skin. My acne scars and sun spots are almost gone and it has visibly reduced my fine lines and wrinkles. I have recommended this product to all my friends and they all love it! It was hard to justify the cost at first but it is worth every penny!

  9. Dasha

    Fantastic for all climates, also great for acne prone skin, doesn’t make me break out

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