The Exceptional Chronobiology Sleep Mask


The Exceptional Chronobiology Sleep Mask is a high-performance treatment that is carefully synchronised to work in synergy with the skin’s natural overnight biorhythm of regeneration and self-repair processes, for a skin transformation overnight.

8 doses x 3.3ml

In stock

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The Exceptional Chronobiology Sleep Mask uses Noble Panacea’s groundbreaking OSMV technology. Furthermore, it provides a results-driven treatment tailored to the skin’s circadian rhythms.

Firstly, the mask is calibrated to release active ingredients at different times throughout your sleep to complement the skin’s natural detox, repair, and absorption processes. Additionally, the treatment features antioxidants, hyaluronic acid, ceramides, retinol, PHAs, pre pro and post-biotics, vitamin C and bakuchiol. What’s more, all of these powerful ingredients help to fight skin aging, uneven skin tone and texture, and restore luminosity.

After an 8 week study with 35 women:

  • 97% said skin looked luminous and radiant
  • 91% said dark spots and pigmentation appear diminished and lightened
  • 89% felt the appearance of deep wrinkles had improved
  • Features high-concentrate active ingredients that are programmed to be released into the skin at prime times throughout the sleep cycle
  • Visibly reduces fine lines, deep wrinkles, and pigmentation
  • Skin is left nourished, detoxified, and balanced
  • Preset doses deliver optimal amount of product to the skin
  • Sustainable starch-based packaging

The Exceptional Chronobiology Sleep Mask works to reduce wrinkles naturally and replenish the skin overnight. Infused with five botanical oils, it provides a deluxe and relaxing experience. Additionally, this overnight face mask decreases TEWL (trans-epidermal water loss), improves the skin barrier, and controls sebum production.

Furthermore, the Exceptional Chronobiology Sleep Mask harnesses the power of OSMV technology to precisely release active ingredients into the skin during the overnight circadian rhythm process. This amplifies the natural detoxifying, reparative, and regeneration processes. As well as this, OSMV protects active ingredients to maintain freshness. Furthermore, it delivers actives with an extended release method to ensure a continual dosage.

Stages of Overnight Circadian Rhythm Process:

Stage 1 is the Detox phase. This takes place from 11 pm-4 am while the skin is eliminating toxins. PHA and pre, pro, and post biotics detoxify, exfoliate and reset the skin.

Stage 2 is the Repair phase. This takes place from 2 am-4 am while cell repair and growth peaks. Retinol and peptides regenerate and rejuvenate the skin.

Stage 3 is the Nourish phase. This occurs from 4 am onwards when the skin’s absorption is at its maximum. Ceramide NP and 2D hyaluronic acid nourish, protect and illuminate the skin.

In summary, this skin plumping treatment naturally reduces signs of aging while protecting the skin. Additionally featured is The Sculptor tool. This allows you to lift and sculpt the skin, further enhancing the benefits of the Noble Panacea Exceptional Chronobiology Sleep Mask. Awaken to healthier and younger-looking skin that has a natural, radiant glow from long-lasting moisturisation.

Clinical Results for the Exceptional Chronobiology Sleep Mask

After 4 weeks:

  • 100% felt skin looked replenished, energised, and healthy-looking
  • 97% said skin felt firm and plumped
  • 94% felt that stressed skin had soothed, with redness and irritation visibly reduced.

After 8 weeks:

  • 97% said skin looked luminous and radiant
  • 91% said dark spots and pigmentation appear diminished and lightened
  • 89% felt the appearance of deep wrinkles had improved.

IDEAL FOR: Deep Wrinkles, Fines Lines, Dark Spots, Hyperpigmentation, Dull Skin, Aging Skin, Stressed Skin & Anti-Aging

SKIN TYPES: Suitable for All Skin Types

Key Ingredients:

Organic Super Molecular Vessel Technology (OSMV): This unique patented delivery system protects and accurately delivers the formula’s active ingredients for perpetual potency and maximum efficacy. It works in four steps. Firstly, OSMV provides ultimate protection – all ingredients are highly protected at their individual molecule level. This ensures freshness and prevents cross contamination. Secondly, OSMV releases active ingredients with extreme precision. Each ingredient is optimised to its unique profile to guarantee maximum absorption by the skin, and therefore increasing skin penetration by over 200%. Thirdly, individual ingredients are delivered in a programmed sequence to maximise their potency. Finally, OSMV delivers ingredients through an extended-release method (based on the ingredient and its benefits). This allows a continual dosage during the healing stage – when it is most powerful and effective. What’s more, OSMV technology increases product penetration and therefore enhances the benefits of other ingredients.

Prebiotics, Probiotics, Postbiotics: This combination of Biotics work to support the skin’s natural microbiome.

Gluconolactone: This PHA (Polyhydroxy Acid) has anti-aging benefits such as reducing wrinkles and increasing skin thickness. As well as this, it helps to remove dead skin cells and has antioxidant properties.

Glycolic Acid: This AHA (Alpha Hydroxy Acid) is a remarkable exfoliator. Glycolic acid benefits include being able to deeply penetrate the epidermis to encourage cellular activity and reduce the appearance of wrinkles.

Lactic Acid: This ingredient is an AHA that increases cell turnover. Lactic acid benefits the skin by improving firmness and minimising fine lines and wrinkles.

Retinol: This powerhouse ingredient has exceptional anti-aging properties. Retinol reduces fine lines and wrinkles by increasing collagen production. Additional retinol skin benefits include fading age spots, unblocking pores, and softening the skin.

Bakuchiol: This skincare ingredient shares similar properties with retinol. Bakuchiol skin benefits include improving brightness, balancing skin tone, wrinkle reduction, and increasing firmness.

Vitamin C: Multiple forms of vitamin C, ascorbyl palmitate, ascorbyl tetraisopalmitate, magnesium ascorbyl phosphate, and ascorbyl glucoside, feature in The Exceptional Chronobiology Sleep Mask. Vitamin C skin benefits include stimulating collagen, brightening the complexion, and preventing premature aging.

Peptides: A collection of peptides feature in The Exceptional Chronobiology Sleep Mask. This includes acetyl hexapeptide-8 (argireline), palmitoyl tripeptide-38, sh-oligopeptide-1, sh-oligopeptide-2, sh-polypeptide-1, sh-polypeptide-11 and sh-Polypeptide-9. Peptides are naturally occurring in the skin; however, they often feature in skincare products due to their soothing, anti-aging, and anti-inflammatory properties. Peptides improve the skin barrier, clear breakouts, calm inflammation, and enhance elasticity.

Ceramide NP: This ceramide helps to retain the skin’s moisture balance. Furthermore, it supports the natural lipid barrier of aging skin. Ceramides' skin benefits include promoting a healthy skin barrier, preventing dryness and irritation, and marinating a firm and plump appearance.

2D Hyaluronic acid: Hydrolysed sodium hyaluronate and sodium hyaluronate are included in the Chronobiology Sleep Mask. Hydrolysed Sodium Hyaluronate is a low-molecular-weight hyaluronic acid. It works to reduce wrinkles and enhance skin elasticity. Sodium Hyaluronate is also low-molecular-weight. It is effective at distributing hydration evenly throughout the skin.

Niacinamide: This ingredient has an abundance of skin benefits. This includes boosting collagen, reducing sebum production, and minimising the appearance of pores.

Coenzyme Q10: This compound is naturally present in the skin and acts as a powerful antioxidant. Therefore, it protects the skin from oxidative damage and prevents premature skin aging.


Water/Eau/Aqua, Argania Spinosa (Argan) Kernel Oil, Glycerin, Oligosaccharide Fatty Acid Esters (OSMV), Squalane, Ascorbyl Glucoside, Lactobacillus Ferment, Sucrose Stearate, Cetearyl Alcohol, Niacinamide, Potassium Cetyl Phosphate, Vitis Vinifera (Grape) Seed Oil, Simmondsia Chinensis (Jojoba) Seed Oil, Dipalmitoyl Hydroxyproline, Alpha-Glucan Oligosaccharide, Propanediol, Rosa Damascena (Rose) Flower Water, Aloe Barbadensis Leaf Juice, Butyrospermum Parkii (Shea) Butter, Jojoba Esters, Stearyl Alcohol, Lactic Acid, Opuntia Ficus-Indica (Prickly Pear) Seed Oil, Nigella Sativa (Black Cumin) Seed Oil, Ceramide NP, Hydrolyzed Sodium Hyaluronate, Sodium Hyaluronate, Retinol, Gluconolactone, Persea Gratissima (Avocado) Oil, Acetyl Hexapeptide-8, Palmitoyl Tripeptide-38, sh-Oligopeptide-1, sh-Oligopeptide-2, sh-Polypeptide-1, sh-Polypeptide-11, sh-Polypeptide-9, Centella Asiatica (Gotu Kola) Leaf Extract, Magnesium Ascorbyl Phosphate, Glycolic Acid, Camellia Sinensis (Green Tea) Leaf Extract, Bakuchiol, Caffeine (Coffea Arabica), Panax Ginseng Root Extract, Acetyl Glutamine, Lecithin, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Allantoin, Xanthan Gum, Carnitine, Rice Amino Acids, Vitis Vinifera (Grape) Seed Extract, Ascorbyl Tetraisopalmitate, Glyceryl Linoleate, Phytic Acid, Ascorbyl Palmitate, Panthenol, Tocopherol, Tocopheryl Acetate, Glyceryl Linolenate, Oryza Sativa (Rice) Bran Extract, Helianthus Annuus (Sunflower) Extract, Rosmarinus Officinalis (Rosemary) Leaf Extract, Ubiquinone, Potassium Hydroxide, Phospholipids, Bacillus/Folic Acid Ferment Filtrate Extract, Hydroxypropyl Cyclodextrin, Caprylyl Glycol, Ethylhexylglycerin, Phenoxyethanol, Sodium Benzoate.

Free from: Phthalates, parabens, silicone, mineral oil GMO’s, SLS & SLES, alcohol, artificial fragrance, nitrates, palm oil, petrolatum, artificial colours, and gluten

Non-comedogenic & dermatologist-approved

Vegan & cruelty-free

Open the Active Dose with the Dose Opener and empty the mask onto the Gua Sha tool. Using the silicone brush applicator, apply the mask directly to your face, neck and eye area. Use the Gua Sha tool to sculpt your facial contours

Apply to cleansed skin 1-2 times weekly. Ensure you apply it as the last step of your skincare routine, just before sleeping.